Thiamine or vitamin B1 is found in many food sources, but they are poorly absorbed in the body. Japanese researchers that were searching for a way to improve absorption of thiamine discovered the supplement sulbutiamine. The supplement can easily move across the blood-brain-barrier and offer all the cognitive benefits that thiamine can provide.
Sulbutiamine, after entering the brain, breaks down into thiamine and other related esters. The supplement increases the concentration of thiamine and thiamine phosphate in the brain. The increase of these two substances confers many cognitive benefits to the user.
The neurotransmitter dopamine responsible for the feeling of pleasure is involved in cognitive functions like focus, learning, motivation, etc. Sulbutiamine increases the levels of dopamine along with the density of dopamine receptors in the brain. When dopamine levels rise in the brain, the user finds it easy to overcome shyness, fight depression, and stay motivated.
Sulbutiamine has considerable influence on other neurotransmitters. Studies prove that the nootropic supplement increases the levels of glutamate.
Sulbutiamine and Neuron Communication: Sulbutiamine promotes communication between brain cells. When neurons effectively communicate with each other the brain becomes more active. This makes the user less fatigued and more alert and focused. Sulbutiamine is widely used to treat asthenia, which is condition characterized by lack of energy and abnormal physical weakness.
Sulbutiamine does an excellent job at promoting neuron communication as well as protecting the neurons in the brain. The nootropic supplement promotes the formation of the fatty white substance called myelin. This substance is essential for protecting the neurons and for the effective functioning of the nervous system.
Sulbutiamine and Memory: The supplement’s ability to influence three of the most important systems in the brain – cholinergic, glutaminergic, and dopaminergic systems, does wonders for memory. Users who take sulbutiamine report improvement in memory, learning, thinking, and reasoning. In a study, Alzheimer’s patients who took donepezil and sulbutiamine fared better in memory tests than those who were given a placebo along with donepezil.
How to Take Sulbutiamine: Taking sulbutiamine in the powder form might not be the best idea, especially for those who are averse to strong tasting supplements. The prudent thing to do here is to make capsules of the sulbutiamine powder.
It’s equally important to remember that sulbutiamine is a fat soluble nootropic supplement. Take your daily dose of sulbutiamine with milk or fish oil, and avoid using the supplement with water or juice. Taking the supplement with fat increases its absorption. In addition, it would be prudent to cycle the dosage to avoid tolerance.
Dosage: 250 – 750 mg per day
|What Sulbutiamine Does|
|Increases thiamine and thiamine phosphate|
|Increases the levels of glutamate|
|Encourages communication between brain cells (neurons)|
|Supports learning and quick thinking|
|Enhances focus, memory, and other cognitive functions|
|Helps overcome shyness, fight depression, and stay motivated|
|Treats diabetic neuropathy, erectile dysfunction, asthenia|