Nootropic Phenibut


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History: In the 1960’s, Russian Professor Vsevolod Perekalin led the team that synthesized the nootropic Phenibut at the A.I. Herzen Leningrad Pedagogical Institute. Later, at the Institute of Experimental Medicine in USSR, the synthetic nootropic underwent thorough testing. The Phenibut nootropic supplement has even been prescribed for Russian Cosmonauts to fight stress without the resulting in drowsiness.

Main Benefits: Phenibut isn’t our typical cognitive enhancing nootropic. More than its cognitive benefits, the supplement is widely used for its influence on the state of mind (i.e.) mood of the individual. Regular use of the nootropic supplement may yield the following benefits:



  • Restful Sleep (Improved quality of sleep)
  • Calmness of mind (reduction in worrisome thoughts and less stressful life)
  • Social Confidence (reduction in social inhibition and overcoming shyness and anxiety)

As a derivative of GABA, Phenibut comes with much of the same effect as the neurotransmitter. The presence of GABA in the brain promotes the feeling of calmness and relaxation. Unfortunately, we cannot use GABA as a supplement in its original form to artificially promote these mood benefits. That’s because, the natural inhibitor has difficulty crossing the blood-brain barrier (BBB). In contrast, the Phenibut nootropic supplement that mimics the functioning of the GABA neurotransmitter is readily absorbed in the body. The supplement behaves just like the neurotransmitter; it binds and activates the same set of receptors.

Apart from its mood support benefits, there is scientific evidence to show that Phenibut improves several cognitive faculties. In a clinical study, participants who were given Phenibut showed signs of improved brain function. It was also found that the nootropic supplement significantly increased communication between the two halves of the brain. The increased brain talk between the two hemispheres is a sign of improved problem solving capabilities, critical thinking, and creativity.

Additionally, there is some scientific evidence to also indicate Phenibut’s positive effects on memory and learning functions. While Phenibut delivers apparent cognitive benefits, the favorable outcome is not because of its direct action, but the result of its inhibitory functions. The nootropic supplement prevents negative thoughts, reduces stress, and fights depression. By freeing you from the loop of negative emotions, Phenibut channels your mind and effort in the right direction and helps you focus. The cognitive benefits of Phenibut come from its interaction with the neurotransmitter Dopamine.

The anti-stress abilities of Phenibut also help in improving the sleep quality. The supplement will make you sleep faster, prevent insomnia, and ensure you get restful sleep and feel refreshed the next day.

Dosage: 250 – 1000 mg per day


What Phenibut Does
Possesses anxiolytic properties
Mimics the function of GABA neurotransmitter
Interacts with neurotransmitter dopamine
Acts as neuroprotective agent
Phenibut Benefits
Reduces stress, anxiety, and promotes calmness
An effective mood enhancer
Improves creativity, critical thinking, and enhances problem solving ability
Improves sleep quality and prevents insomnia and other sleep disorders
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