Hesperidin

Hesperidin isn’t naturally produced in the body; the flavonoid is absorbed from fruits (found in abundance in unripe citrus fruits) or supplements.

Hesperidin as an anti-aging supplement: Chemical reactions leave residue in the form of free radicals, which damage DNA, cells, and other elements in the body. Free radicals need to be neutralized periodically to prevent oxidative stress. As we age, the oxidants present in the body become less effective, thereby giving a free hand to the free radicals to damage the cells and cause various disorders such as heart disease, cancer, etc.

The antioxidant and anti-inflammatory properties in hesperidin kill the free radicals, prevent oxidative stress, and protect the blood cells, cell membranes, proteins, DNA, and tissues.

Hesperidin for heart health: Hesperidin helps maintain heart health by reducing the various risk factors that lead to heart disease. The various beneficial properties of hesperidin regulate cholesterol, fat levels, blood pressure, and blood glucose level. They also combat oxidative stress and inflammation to protect the heart tissue.

Hesperidin for cognitive health: Hesperidin again relies on its antioxidant properties to protect the brain from damages of oxidative stress. Scientists found that, in rats, a sugar – D-galactose – disrupted mitochondrial function and killed the nerve cells. The rats were then treated with curcumin and hesperidin. The scientists found the treatment prevented nerve cell death by protecting them from the actions of the sugar D-galactose.

Other studies also fueled the idea that hesperidin could protect memory and other cognitive faculties from a stroke. In a study, hesperidin (50 mg/kg) administered to rats for 15 days protected brain function by reducing free radicals and inflammation. In another study, L-arginine along with hesperidin prevented memory loss in rats that suffered from a stroke.

Hesperidin to fight stress, anxiety, and depression: Relief from stress, anxiety, and depression could have implications on several faculties. Firstly, by improves mood, avoiding and treating these three problems, the supplement can help focus, and improve attention and concentration. In addition, a solution to these three problems could improve the overall physical and psychological health.

Better quality sleep is a significant benefit that regular use of the hesperidin supplement can yield. Hesperidin ensures the users enjoy restful sleep by preventing stress and anxiety and promoting relaxation.

Other Health Benefits of Hesperidin: The flavonoid with its many beneficial properties helps in the treatment of cancer, regulates carbohydrate and fat metabolism to aid weight loss, helps relieve pain, treats allergies, improves skin health, boosts blood circulation, prevents osteoporosis, and improves bone health. In combination with other flavonoids, hesperidin helps treat hemorrhoids.

Dosage: Analysis of the multiple studies involving hesperidin shows the standard dosage is about 500 mg per day. The lowest dosage that can deliver benefits in humans is about 4 mg/kg.

Side Effects: Hesperidin is safe, non-toxic, and almost free of any drug interaction. Side effects are rare and even if they occur the effects are mild. The most common adverse reactions include nausea, vomiting, allergic reactions (itching, hives, etc.) and diarrhea.