Why use a stack that has a limited scope? Why stop with just one cognitive capability? As said above, the stack mentioned here will have a positive impact on several cognitive functions. To make this nootropic stack, only the best supplements have been chosen. Numerous studies have been conducted on these supplements; the nootropics mentioned here do not neutralize or counteract with one another. They synergize with each other and offer the best benefits to the user.
Even though each component of this nootropic stack has a role to play in the outcome, the three main pillars that support the powerful combination arecaffeine, coluracetam, and aniracetam. These three nootropic supplements do the lion’s share of the work in the group.
As you can see, we have tagged modafinil as optional. The circumstance must dictate the use of modafinil. Lack of sound sleep or sleep deprivation are two good reasons to use Modafinil occasionally. Avoid taking the stimulant every day as regular use may lead to tolerance. Although research data don’t support the tolerance claim, many users of this stack have reported diminished modafinil benefits with regular use. Do not take modafinil daily; use it 2-3 times a week.
Part of the racetam group, piracetam is found to improve many faculties such as creativity, learning, memory, and verbal fluency. For optimal result, the ideal dose of this supplement is 4.8g per serving; twice or thrice a day. The exact mechanism of action of piracetam is not fully known, but experts say the nootropic supplement regulates acetylcholine and glutamate levels in the brain.
Although aniracetam and piracetam belong to the same racetam nootropic family, the mechanism of action of both these supplements is vastly different. It’s believed that aniracetam influences our cognitive functions by acting on dopamine D2, nicotinic acetylcholine, and 5-HT2A receptors. Regular use of aniracetam will decrease anxiety, remove brain fog, improve mood, and enhance the ability to focus on the task at hand.
Coluracetam is the third racetam of this stack. It’s to be taken sublingually,placed under the tongue for better absorption into the bloodstream. Studies have found that coluracetam maximizes the use of acetylcholine neurotransmitter in the brain. Users of coluracetam have experienced improved energy, better vision, less depression, and improved mood. As part of this stack, coluracetam increases the efficiency of alpha-GPC.
Caffeine antagonizes all types of AR (adenosine receptors). Moreover, in the striatum, it has been found that caffeine increases the activity of dopamine. Caffeine influences dopamine by increasing d2 and d3 receptors. Caffeine in coffee perks us up and gives a perfect start to our day. But, its benefits go much beyond that. Caffeine as a nootropic supplement enhances our mood, induces wakefulness, and increases energy in the body.
We’ve all experienced the calming and relaxing effect of tea (both green and black). The soothing effect is largely due to the presence of L-theanine. The main role of this amino acid in the brain is to increase the release of dopamine and GABA.
People who take caffeine in the form of a pill or coffee must use L-theanine. We all know and have experienced the anxiety increasing nature of caffeine. To counter this effect of caffeine and calm our body L-theanine is added to this stack. Improving focus and decreasing anxiety are the two main benefits offered by L-theanine.
Although racetams offer great benefits to the brain they are not without side effects. Racetams reduce the levels of acetylcholine neurotransmitter in the brain. Doing so usually results in memory impairment, brain fog, and headache. To counteract the side effects of racetams in this stack, we have added alpha-GPC. Alpha-GPC performs two functions in this stack. It increases choline levels and enhances the ability to learn and remember (memory).
Agmatine influences several neurotransmitters in the brain, but it has been added to this stack to perform a specific function – to act as NMDA antagonist. Some of the other supplements in this stack might increase glutamate in the brain. Too much of glutamate activity can result in neurotoxicity. Agmatine will reduce the risk of neurotoxicity.
Additionally, agmatine also helps in preventing caffeine and modafinil tolerance. Other benefits of agmatine include treating depression and increasing confidence.
Noopept is a powerful nootropic supplement derived from piracetam. Noopept is a derivative of racetam, but it’s not a racetam. It has a totally different mechanism of action. Studies have found noopept to increase brain-derived neurotrophic factor and nerve growth factor. Noopept is widely used to improve long-term memory. It does not produce immediate results. Stick to this supplement, you’ll see good results after a few weeks.
Modafinil is similar to caffeine, but its effects are longer. Experts are still not fully clear on the efficiency and side effects of modafinil. Some studies have found the stimulant to be helpful in improving cognition in ADHD patients. Other health benefits of modafinil include improvement in logical thinking, reducing sleepiness, and increasing motivation.